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Stem CellsImmune SystemLymphomaBiologyBrain TumorLung Cancer
Immune Cells Use 'Bungee of Death' to Kill Dangerous Cells, New Research Shows
March 27, 2010 — Immune cells ensnare dangerous cells that are on the run with a bungee-like nanotube, according to new research. The study shows that natural killer cells use this bungee to destroy cells that could ... > full story
Breast CancerWomen's HealthCancerMenopauseColon CancerDiseases and Conditions
MRI Finds Tumors in Second Breast of Women Diagnosed With Cancer in One Breast, Study Suggests
March 27, 2010 — Postmenopausal women, including those over 70 years old, who have been newly diagnosed with cancer in one breast have higher cancer detection rates when the other breast is scanned for tumors with ... > full story
Gender DifferenceSocial PsychologyEducational PolicyChild DevelopmentChild PsychologyPsychology
Pursuit of Status and Affection Drives Bullies' Behavior
March 27, 2010 — A longitudinal study of almost 500 Dutch elementary-school children ages 9 to 12 finds that bullies generally choose to gain status by dominating their victims and that, at the same time, bullies try ... > full story
MemoryIntelligenceDementiaEducational PsychologyPsychologyNeuroscience
Of Mice and Memory: 'Working Memory' of Mice Can Be Improved
March 27, 2010 — Mice trained to improve their working memory become more intelligent, suggesting that similar improvements in working memory might help human beings enhance their brain power, according to new ... > full story
New SpeciesNatureBiochemistry ResearchExotic SpeciesBiologyInsects (and Butterflies)
Hidden Habits and Movements of Insect Pests Revealed by DNA Barcoding
March 27, 2010 — Researchers have found a faster way to study the spread and diet of insect pests. Using a technique called DNA barcoding, which involves the identification of species from a short DNA sequence, they ... > full story
DiabetesHormone DisordersFitnessPersonalized MedicineObesityChronic Illness
New Alterations Found in Young Adults With Type 2 Diabetes
March 27, 2010 — Diet and aerobic exercise are highly effective for the treatment of type 2 diabetes, but not for obese subjects that have developed the disease when very young. A new study demonstrates that obese ... > full story
NanotechnologyDetectorsMaterials ScienceBatteriesElectronicsChemistry
A More Sensitive Sensor
March 27, 2010 — Scientists have set out to make sensors for microelectromechanical systems significantly more sensitive and reliable than they are today, shrinking their work to nano-size to do ... > full story
MemoryIntelligenceMental HealthBrain InjuryNeurosciencePsychology
Older Adults Remember the Good Times: Changes in Brain Connectivity With Aging May Enable Older Adults to Remember Positive Events
March 27, 2010 — Despite the aches and pains that occur in old age, many older adults maintain a positive outlook, remembering the positive experiences from their ... > full story
Molecular BiologyGeneticsBiologyBiotechnologyBehavioral ScienceCell Biology
Behavior of Single Protein Observed in Unprecedented Detail
March 27, 2010 — Scrutinizing a single molecule for more than a few milliseconds used to require effectively "stapling" it down, inhibiting its normal behavior. Now, using a newly developed technique, chemists have ... > full story
LeukemiaColon CancerCancerLymphomaSkin CancerProstate Cancer
New Gateway to Treat Leukemia and Other Cancers
March 27, 2010 — Researchers have discovered a previously hidden channel to attack leukemia and other cancer cells, according to a new study. The findings may change the way doctors treat cancer ... > full story
Search ScienceDaily
Number of stories in archives: 83,395
view headlines only
Stem CellsImmune SystemLymphomaBiologyBrain TumorLung Cancer
Immune Cells Use 'Bungee of Death' to Kill Dangerous Cells, New Research Shows
March 27, 2010 — Immune cells ensnare dangerous cells that are on the run with a bungee-like nanotube, according to new research. The study shows that natural killer cells use this bungee to destroy cells that could ... > full story
Breast CancerWomen's HealthCancerMenopauseColon CancerDiseases and Conditions
MRI Finds Tumors in Second Breast of Women Diagnosed With Cancer in One Breast, Study Suggests
March 27, 2010 — Postmenopausal women, including those over 70 years old, who have been newly diagnosed with cancer in one breast have higher cancer detection rates when the other breast is scanned for tumors with ... > full story
Gender DifferenceSocial PsychologyEducational PolicyChild DevelopmentChild PsychologyPsychology
Pursuit of Status and Affection Drives Bullies' Behavior
March 27, 2010 — A longitudinal study of almost 500 Dutch elementary-school children ages 9 to 12 finds that bullies generally choose to gain status by dominating their victims and that, at the same time, bullies try ... > full story
MemoryIntelligenceDementiaEducational PsychologyPsychologyNeuroscience
Of Mice and Memory: 'Working Memory' of Mice Can Be Improved
March 27, 2010 — Mice trained to improve their working memory become more intelligent, suggesting that similar improvements in working memory might help human beings enhance their brain power, according to new ... > full story
New SpeciesNatureBiochemistry ResearchExotic SpeciesBiologyInsects (and Butterflies)
Hidden Habits and Movements of Insect Pests Revealed by DNA Barcoding
March 27, 2010 — Researchers have found a faster way to study the spread and diet of insect pests. Using a technique called DNA barcoding, which involves the identification of species from a short DNA sequence, they ... > full story
DiabetesHormone DisordersFitnessPersonalized MedicineObesityChronic Illness
New Alterations Found in Young Adults With Type 2 Diabetes
March 27, 2010 — Diet and aerobic exercise are highly effective for the treatment of type 2 diabetes, but not for obese subjects that have developed the disease when very young. A new study demonstrates that obese ... > full story
NanotechnologyDetectorsMaterials ScienceBatteriesElectronicsChemistry
A More Sensitive Sensor
March 27, 2010 — Scientists have set out to make sensors for microelectromechanical systems significantly more sensitive and reliable than they are today, shrinking their work to nano-size to do ... > full story
MemoryIntelligenceMental HealthBrain InjuryNeurosciencePsychology
Older Adults Remember the Good Times: Changes in Brain Connectivity With Aging May Enable Older Adults to Remember Positive Events
March 27, 2010 — Despite the aches and pains that occur in old age, many older adults maintain a positive outlook, remembering the positive experiences from their ... > full story
Molecular BiologyGeneticsBiologyBiotechnologyBehavioral ScienceCell Biology
Behavior of Single Protein Observed in Unprecedented Detail
March 27, 2010 — Scrutinizing a single molecule for more than a few milliseconds used to require effectively "stapling" it down, inhibiting its normal behavior. Now, using a newly developed technique, chemists have ... > full story
LeukemiaColon CancerCancerLymphomaSkin CancerProstate Cancer
New Gateway to Treat Leukemia and Other Cancers
March 27, 2010 — Researchers have discovered a previously hidden channel to attack leukemia and other cancer cells, according to a new study. The findings may change the way doctors treat cancer ... > full story
Search ScienceDaily
Number of stories in archives: 83,395
Building a Better Mouse
A notoriously poor proxy for the human experience of cancer, mouse models are now undergoing a major renovation. EDYTA ZIELINSKA asks: Can a new multimillion dollar project find a mouse model that can help patients and save companies millions on drugs that are destined to fail?
Related Articles
Three New Paradigms
The Trouble With Animal Models
Of Men, Not Mice
Master of the Cell
RNA interference, with its powerful promise of therapy for many diseases, may also act as a master regulator of most-if not all—cellular processes, according to JUDY LIEBERMAN, senior investigator at Children's Hospital Boston and a professor of pediatrics at the Harvard Medical School.
Related Articles
More Support for RNAi in Clinic
Targeting with siRNAs
A Nuanced Knockout
Against the Element
Grisly research in the Arctic is causing some scientists to wonder: Is there no safe level of mercury? ELIE DOLGIN flew 1500 kilometers north of Montreal (where the wind chill made it roughly-35°C) to find out more.
Related Articles
Beluga Blight
Shark RxRead more: The Scientist : Table of Contents : April 2010 http://www.the-scientist.com/toc/2010/4/#ixzz0jNIPE6cgRead more: The Scientist : Table of Contents : April 2010 http://www.the-scientist.com/toc/2010/4/#ixzz0jNIPJ9Qf
Posted by Lauren Urban
[Entry posted at 19th March 2010 03:14 PM GMT]
View comments(2) Comment on this news story
What do a yam, a wasp, and a wallaby all have in common? Well, not much, actually, but they're all being touted as the next big experimental model, according to a new laboratory manual due out in April. The second volume of Emerging Model Organisms, from the Cold Spring Harbor Laboratory Press, examines a range of organisms -- some familiar, some not -- that could soon be coming to a lab near you.
Image:Cold Spring Harbor Laboratory PressRichard Behringer, an editorial adviser for the book and developmental geneticist at University of Texas M.D. Anderson Cancer Center, told The Scientist that he hopes the book will help present alternative model organisms that have different strengths than ones currently popular within the scientific community. "Research is dominated by a small number of model organisms," Behringer said, listing the usual suspects (mice, chicks, frogs, etc.) as examples. The book consist of chapters written by researchers using a particular organism in their own lab and includes "some basic protocols and some pointers showing where more detailed information can be found," wrote David Crotty, an executive editor at the Cold Spring Harbor Laboratory Press, in an e-mail to The Scientist. Each chapter introduces the reader to a model organism and includes background information about related species, genetics, and pointers on how to raise or obtain the organism. The chapter also describes several laboratory procedures using each organism. "Our goal is to continue exposing as many of these systems as possible, creating a resource that provides some quick answers as to the strengths and weaknesses of an unfamiliar system," continued Crotty. Crotty said that he sees this second edition as a continuation of the first, which discussed the viability of using organisms such as bats, butterflies, and snapdragon, and that there are plans for more editions to be released in the future. "Since there are a near-infinite number of interesting experimental questions to be asked," there are a "correspondingly large number of potential model organisms." Behringer, who studies mammalian genetics, said he wanted to make sure that "vertebrates and especially mammals are well represented" in this edition. He helped to select wallabies as models for embryonic development, rabbits as models for mammalian reproduction and early embryology, and the painted turtle as a model for vertebrate evolution, for this edition. In his work, he has used rats and bats, in addition to mice, to aid in understanding embryogenesis. Behringer found that mice had some limitations that other laboratory animals did not have, and he said that other mammals provide "scientifically interesting" data, for example rabbits can be used for antibody production, as well as serving as models for in vitro fertilization. Crotty added that with the cost of sequencing becoming less expensive and technologies improving, more laboratories are choosing organisms that more precisely suit their needs. While the title of the new manual suggests that all the organisms in the book are novel, some are already being used in labs around the world. For example, the wallaby, a small kangaroo-like marsupial, has been thoroughly studied as a model for reproduction and development in its native Australia. However, the concept of replacing Drosophila with wallabies may be unfamiliar to American scientists. However, the wallaby's genome is being assembled, and their importance as a model organism should not be underestimated, according to Behringer. Even the editors of Emerging Model Organisms were fascinated by some of the models proposed. Behringer was intrigued by the Hawaiian bobtail squid, which serves as a model for mutualism (it maintains a symbiotic relationship with a species of bacteria that produces light for the organism), for cephalopod development, and for morphological innovations. Comparisons can be made between the light organ and mammalian eyes, said Margaret McFall-Ngai, an animal developmental biologist at the University of Wisconsin-Madison. Read more: Supermodels? - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/blog/display/57225/#ixzz0jNHs7BZj
News:
Creature castPosted by Lauren Urban
[Entry posted at 26th March 2010 02:40 PM GMT]
View comment(1) | Comment on this news story
Most university professors have ideas for how to get their students excited about the science they're studying -- rarely do those plans involve claymation. Unless, of course, you happen to be Brown University evolutionary biologist Casey Dunn's student.
"Nature documentaries like 'Blue Planet' and 'Planet Earth' were a big part of what got me interested in science, and it was fun to kind of ape the best parts of existing nature documentaries while giving it a more manageable sort of modular internet spin," says Noah Rose, an undergraduate biology major at Brown who took Dunn's invertebrate zoology class.
Along with Rose and other students who take the semester-long course, about five other undergrads and graduate students mentored by Dunn regularly contribute to "Creaturecast", a blog born out of a collaborative National Science Foundation grant on mollusk evolutionary relationships awarded to Dunn in 2008. As part of that grant, Dunn needed to demonstrate the broader impact of his research, and he decided to add a blog to his lab website to help communicate his work to the general public. Rose says that the blog is "a way to get excited about animals" and that it "provides a sort of wide ranging, integrative, and aesthetic approach to nature that you can't get from a lot of sources."
Dunn uses the blog as a teaching tool in his classroom and requires students to create an episode of "Creaturecast" as a final project. Rose created a video post on marine worms as his final project last fall. He interviewed a number of people for the video, including graduate students, a microbiologist, and a local bait shop employee. The post wriggles with footage of worm movement and animations created by Rose. He says that finding the right balance of entertainment and information in the video was challenging, as it was "easy to say nothing," and equally easy to say "too much."
Read more: Creature cast - The Scientist - Magazine of the Life Sciences http://www.the-scientist.com/blog/display/57262/#ixzz0jNHJ3nxq
